Our unit utilises contemporary molecular biological techniques (such as silencing RNA and gene knockout models) and are experts in cell isolation from sections of pulmonary arteries. Our research aims to understand and address changes in vessel wall make-up on a cellular level which contribute to the pathology of pulmonary hypertension. Translational research is very important within the Scottish Pulmonary Vascular Unit and we are undertaking studies which crosses from bench to bedside with regards to interesting and novel molecules aimed ultimately at disease targeted therapy.