BASIC SCIENCE

Complementing patient care and clinical research, the Scottish Pulmonary Vascular Unit has adopted basic science research since the 1990s in an attempt to understand the profound changes of pulmonary arteries in patients with pulmonary hypertension.

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Our unit utilises contemporary molecular biological techniques (such as silencing RNA and gene knockout models) and are experts in cell isolation from sections of pulmonary arteries. Our research aims to understand and address changes in vessel wall make-up on a cellular level which contribute to the pathology of pulmonary hypertension. Translational research is very important within the Scottish Pulmonary Vascular Unit and we are undertaking studies which crosses from bench to bedside with regards to interesting and novel molecules aimed ultimately at disease targeted therapy.

Our work is funded by medical charities i.e. British Lung Foundation, Chest, Heart and Stroke Scotland and the British Heart Foundation, all of whom actively seek solutions to this medical condition.

Staff within the SPVU Laboratory:
· Section Leader – Dr David Welsh.
· Consultant Physician / NES Research Fellow – Dr Colin  Church.

 

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Previous publications are listed here

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